Sense

1. sad at heart, sorrowful, melancholy
2. ill-disposed, malignant
3. insensate

Examples

• ὕπαστρον δέ τοι μῆχαρ ὁρίζομαι γάμου δύσφρονοσ φυγάν· (Aeschylus, Suppliant Women, choral, strophe 32)
• ὤμοι δύσφρονοσ ἄτασ. (Sophocles, Oedipus at Colonus, choral, antistrophe 210)
• δύσφρων γὰρ ἰὸσ καρδίαν προσήμενοσ ἄχθοσ διπλοίζει τῷ πεπαμένῳ νόσον, τοῖσ τ’ αὐτὸσ αὑτοῦ πήμασιν βαρύνεται καὶ τὸν θυραῖον ὄλβον εἰσορῶν στένει. (Aeschylus, Agamemnon, episode, anapests 3:4)

Source: Henry George Liddell. Robert Scott. "A Greek-English Lexicon". revised and augmented throughout by. Sir Henry Stuart Jones.